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Home>>Products>>Clearance Sale: 98% Purity API Powder CAS 305-03-3 C14H19Cl2NO2 Chlorambucil

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Clearance Sale: 98% Purity API Powder CAS 305-03-3 C14H19Cl2NO2 Chlorambucil

CAS NO.305-03-3

  • msdsMSDS/COA Download

  • FOB Price: USD: 7.00-15.00 /Gram Get Latest Price
  • Min.Order: 10 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
  • Available Specifications:

    pharmaceutical grade(10-50)Grampharmaceutical grade(50-100)Grampharmaceutical grade(100-1000)Grampharmaceutical grade(1000-10000)Gram

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Product Details

Keywords

  • Chlorambucil
  • Chlorambucil API
  • 305-03-3

Quick Details

  • ProName: Clearance Sale: 98% Purity API Powder ...
  • CasNo: 305-03-3
  • Appearance: white powder
  • Application: treat chronic lymphocytic leukemia
  • DeliveryTime: 15 working days
  • PackAge: poly bag + foil bag
  • Port: shanghai; shenzhen, hongkong
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 98% HPLC
  • Storage: RT
  • Transportation: express via fedex, dhl, ems,etc
  • LimitNum: 10 Gram
  • Related Substances: Chlorambucil
  • Residue on Ignition: ≤0.1%
  • Heavy Metal: ≤20ppm
  • Valid Period: 24 months

Superiority

Clearance Sale: 98% Purity API Powder CAS 305-03-3 C14H19Cl2NO2 Chlorambucil

Chlorambucil is a nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens;

Chlorambucil is an Alkylating Drug. The mechanism of action of chlorambucil is as an Alkylating Activity;

Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.

Details

Chlorambucil is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma.  For CLL it is a preferred treatment. It is given by mouth.

 
Common side effects include bone marrow suppression. Other serious side effects include an increased long term risk of further cancer, infertility, and allergic reactions.  Use during pregnancy often results in harm to the baby. Chlorambucil is in the alkylating agent family of medications. It works by blocking the formation of DNA and RNA.
 
Chlorambucil was approved for medical use in the United States in 1957. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. 
 
Chlorambucil's current use is mainly in chronic lymphocytic leukemia, as it is well tolerated by most patients, though chlorambucil has been largely replaced by fludarabine as first-line treatment in younger patients. It can be used for treating some types of non-Hodgkin lymphoma, Waldenström macroglobulinemia, polycythemia vera, trophoblastic neoplasms, and ovarian carcinoma. Moreover, it also has been used as an immunosuppressive drug for various autoimmune and inflammatory conditions, such as nephrotic syndrome.
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