Keywords

• Sofosbuvir powder
• Sofosbuvir
• 99% Sofosbuvir powder

Quick Details

• ProName: cas 1190307-88-0 99% Sofosbuvir powder
• CasNo: 1190307-88-0
• Molecular Formula: C37H42F2N8O4
• Appearance: white
• Application: anti antiviral
• DeliveryTime: 7-10 days
• PackAge: drum
• Port: Shanghai/Wuhan
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99
• Storage: room
• LimitNum: 100 Gram

Superiority

Details

cas 1190307-88-0 99% Sofosbuvir powder 

Sofosbuvir is a drug used for the treatment of hepatitis C. It is recommended to be used in combination with other drugs for the first-line treatment for HCV genotypes 1, 2, 3, 4, 5, and 6. It takes effect through acting as a nucleotide analog inhibitor, being capable of specially inhibiting the HCV NS5B (non-structural protein 5B) RNA-dependent RNA polymerase.

PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus  . PSI-7977 is effective in vitro and in vivo.
PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the t reatment of hepatitis C. 
Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.