Country: China (Mainland)
Business Type:Trading Company
Tel: +86 27 84492310
Tel: WhatsApp +8615927784577
Street: FANHU INDUSTRY PARK
Vanz Pharm, which is specialized in custom synthesis and R&D, is located in Wuhan, China. our main products are indacaterol, carmoterol etc. We have established long-term cooperation with Shanghai Institute of Organic Chemistry, Wuhan University etc. As a special team in organic chemistry and medicinal chemistry, we support the technology of R&D on new product. We have strong advantages on the process research and product R&D, pay attention to researching and developing new technology which is self-owned intellectual property right. We are special at developing Drug for the respiratory, antidepressant, antivirus. We have completed R&D of more than 20 APIs and intermediates after the company founded.
Our R&D center covers an area of 1000 square meters, with four synthesis labs, one scale-up pilot labs and one analytical lab. The lab is equipped with complete laboratory facilities and equipment. We have a professional research team of highly qualified and experienced chemists. most of our R&D team are Master and higher. With their effort, we quickly transfer the science fruit into production. Our manufacturing site is located in Wuhan which is equipped with 100L~5000L reactors; we can offer one-stop services from R&D to commercial production. (Normal reaction/ High-pressure reaction/ Catalytic reaction/ Low-Temperature reaction).
With great joint efforts of our staffs, Vanz is getting more market for developing and manufacturing Medicine, New Compounds, Advanced Intermediates, as well as Custom Synthesis. We will make persistent efforts, providing excellent services to our customers, perfecting R&D condition, as well as enlarging business service range. We believe Vanz will be one of the brightest star in near future with your kind support and our mutual efforts.
Product Name: Tianeptine sodium salt
Mol File: 30123-17-2.mol
Tianeptine Sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Medical uses of Tianeptine sodium
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects,thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs.Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).