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CAS NO.41100-52-1
cas 41100-52-1 99% Memantine HCl powder
Product Name: Memantine HCl
CAS: 41100-52-1
MF: C12H22ClN
MW: 215.76
EINECS: 255-219-6
Product Name: Memantine HCl
CAS: 41100-52-1
MF: C12H22ClN
MW: 215.76
EINECS: 255-219-6
Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer’s disease. It is believed to be the first neuroprotective drug that has achieve clinical . The development of Alzheimer’s disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington’s disease, ALS and movement disorders, among other.