Keywords

• 6-Mercaptopurine monohydrate
• 6-Mercaptopurine monohydrate powder
• 99% 6-Mercaptopurine monohydrate

Quick Details

• ProName: cas 6112-76-1 99 % puriy 6-Mercaptop...
• CasNo: 6112-76-1
• Molecular Formula: C14H4N2Na2O8
• Appearance: white
• Application: anti aging
• DeliveryTime: 7-10 days
• PackAge: drum
• Port: Shanghai/Wuhan
• ProductionCapacity: 1000 Kilogram/Month
• Purity: 99
• Storage: room
• LimitNum: 10 Gram

Superiority

 cas 6112-76-1   99 % puriy 6-Mercaptopurine monohydrate  powder  

Details

cas 6112-76-1   99 % puriy 6-Mercaptopurine monohydrate  powder  

Product Name:    6-Mercaptopurine monohydrate
CAS:    6112-76-1
MF:    C5H6N4OS
MW:    170.19
EINECS:    612-090-4

6-Mercaptopurine (6-MP) is an inhibitor of purine synthesis and interconversion. It is rapidly converted to 6-mercaptopurine ribonucleoside-5''-monophosphate, which inhibits phosphoribosyl pyrophosphate (PRPP) amidotransferase, the rate-limiting enzyme in purine synthesis. It also inhibits the conversion of IMP to adenylosuccinic acid and xanthylic acid and blocks AMP formation in vitro. 

6-MP inhibits growth of sarcoma 180, adenocarcinoma E 0771, and adenocarcinoma 755 tumors and reduces the size of leukemia L1210 subcutaneous growths in mice. It also decreases delayed-type hypersensitivity and thyroid inflammation in a guinea pig model of thyroiditis when administered pre- or post-disease onset. Formulations containing mercaptopurine have been used for maintenance therapy in patients with acute lymphoblastic leukemia.