Keywords

• Trimebutine
• Trimebutine powder
• 99% Trimebutine

Quick Details

• ProName: Anti-Ulcer API Pharm Grade CAS 39133-3...
• CasNo: 63968-64-9
• Molecular Formula: C15H22O5
• Appearance: white
• Application: Artemisia annua is used as antimalaria...
• DeliveryTime: 7-10 days
• PackAge: drum
• Port: Shanghai/Wuhan
• ProductionCapacity: 1000 Kilogram/Month
• Purity: 99
• Storage: room
• LimitNum: 1 Kilogram

Superiority

Anti-Ulcer API Pharm Grade CAS 39133-31-8 99% Trimebutine Powder  

Details

Anti-Ulcer API Pharm Grade CAS 39133-31-8 99% Trimebutine Powder  

What is Trimebutine
Trimebutine is a drug used to treat gastrointestinal symptoms and irritable bowel syndrome caused by chronic gastritis. It is a non-competitive antispasmodic drug with mild opioid receptor affinity and significant anti-serotonin effect, which can regulate spontaneous movement of the gastrointestinal tract, increase electrophysiological stimulation and contraction of isolated guinea pig large intestine and ileum synchronicity.

Trimebutine Function
Trimebutine is a regulator of gastrointestinal motility rhythm, which has two-way regulation of excitation and inhibition on gastrointestinal motility. When the digestive tract is in a state of low exercise, trimebutine can inhibit the potassium ion channel of the cell membrane, resulting in depolarization, thereby exciting the smooth muscle of the gastrointestinal tract and restoring the normal state of gastrointestinal motility, while when the digestive tract is in a state of exercise excitation , then act on cholinergic neurons, inhibit the release of acetylcholine, thereby inhibiting the excessive movement of the gastrointestinal tract, so that the disordered gastrointestinal function is regulated. In addition, trimebutine can also stimulate opioid receptors and promote the release of gastrointestinal peptides, thereby inhibiting gastrointestinal pain nerve reflex, reducing abdominal pain, and can also play a certain antiemetic effect.