Keywords

• Veliparib
• Veliparib Dihydrochloride powder
• 99% Veliparib Dihydrochloride

Quick Details

• ProName: Veliparib Dihydrochloride Abt-888 cas ...
• CasNo: 912445-05-7
• Molecular Formula: C15H22O5
• Appearance: white
• Application: Artemisia annua is used as antimalaria...
• DeliveryTime: 7-10 days
• PackAge: drum
• Port: Shanghai/Wuhan
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99
• Storage: room
• LimitNum: 1 Kilogram

Superiority

Veliparib Dihydrochloride Abt-888 cas 912445-05-7 

Product Name:    Veliparib Dihydrochloride
 CAS: 912444-00-9
MF: C13H16N4O.2ClH
MW: 317.218

Details

Veliparib Dihydrochloride Abt-888 cas 912445-05-7 

Product Name:    Veliparib Dihydrochloride
 CAS: 912444-00-9
MF: C13H16N4O.2ClH
MW: 317.218 

Veliparib  is a potent PARP1 and PARP2 inhibitor with Ki of 5.2nM and 2.9nM, respectively, inhibiting SIRT2.Phase3.ABT-888 effectively inhibited PARP, and the Ki value of PARP-1 and PARP-2 was 5.2 nM and 2.9nM, respectively.ABT-888 decreased the survival rate of cloned genes in lung cancer H460 cells and inhibited DNA repair.ABT-888 inhibited C41 cells with an EC50 of 2nM.ABT-888 is used in combination with radiation to reduce tumor angiogenesis.