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CAS NO.936091-26-8
cas 936091-26-8 Fedratinib powder
Product Name: | Fedratinib |
CAS: | 936091-26-8 |
MF: | C27H36N6O3S |
MW: | 524.68 |
What is Fedratinib
Fedratinib is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35-and 334-fold more selective for JAK2 versus JAK1 and JAK3. Phase 2. A potent, highly selective and ATP-competitive JAK2 inhibitor with an IC50 of 3 nM for JAK2 and JAK2V617F.
Fedratinib function
TG101348 is a selective inhibitor of JAK2 tyrosine kinase. Potent JAK2 inhibitor.